| Title |
Primary Class |
Description |
Inventors |
Assignee |
Issue Date |
Patent No. |
| Glandular extractive product |
A61K31/573 |
A new and useful Glandular Extractive Product that relates to a new and useful product which possesses in a stable, permanent, and concentrated form the hemostatic blood-pressure-raising astringent and other physiological reactions and characteristics of the suprarenal capsules or glands, particularly those which affect the muscular system and muscular walls of the blood Vessels. |
Jokichi Takamine |
___ |
November 5, 1900 |
US730176A |
| Method for synthesis of oxyphenyl-isopropylamine (translated from German) |
12q/32 (old German) |
Synthesis of oxyphenyl-isopropylamine (related to adrenaline) (translated from German) |
Karl W. Rosenmund; Carl Mannich; Willy Jacobsohn |
___ |
October 21, 1909 |
DE243546 |
| Method for synthesis of phenylalkylamines (translated from German) |
12q/32 (old German) |
Synthesis of phenylalkylamines (includes adrenaline) (translated from German) |
Karl W. Rosenmund; Carl Mannich; Willy Jacobsohn |
___ |
October 21, 1909 |
DE247906 |
| Manufacture of physiologically active substances from the anterior lobes of the hypophysis |
A61K38/24 |
Treating the fresh anterior lobes of the hypophysis separately with an organic solvent capable of dissolving lipoids, such as acetone, in order to obtained therapeutically active substances |
IG Farbenindustrie AG |
___ |
September 23, 1929 |
GB291018 |
| Process of preparing physiologically active extracts from the anterior lobes of the hypophysis |
435/268 |
Improvement of the strength of the aqueous extracts that are obtained in the production of the estrous promoting product |
Ludwig, Lautenschlager Carl; Fritz, Lindner |
Winthrop Chemical Company, Inc., New York |
July 31, 1934 |
US1968156 |
| Anesthetic combinations containing, besides a local anesthetic agent, a vasoconstricting agent |
514/536 |
Improving anesthetic combinations, containing epinephrine, toxic by product effects |
Max Bockmuhl; Otto Schaumann; Gustav Ehrhart; Leonhard Stein |
Winthrop Chemical Company, Inc., New York |
September 22, 1936 |
US2055064 |
| Stabilized epinephrine-type compound and process stabilizing it |
562/74 |
Stabilization epinephrine by using organic thiol acids, mercaptan and tautomeric substances |
Morris S. Kharasch |
Eli Lilly and Company, Indianapolis |
July 7, 1936 |
US2047144 |
| Manufacture of stable derivative of adrenaline |
549/316 |
A new compound of adrenaline and ascorbic acid in the presence of an inert organic solvent |
Hoffmann et al. |
Byk, Guldenwerke Chem Fab A. G. |
August 27, 1940 |
US2212831 |
| Method for the purification of extracts containing the adrenal cortical hormone |
424/563 |
Efficient method of separating the accompanying lipid-like substances and adrenaline from the adrenal cortical hormone |
Alois Detzel |
Chemische Fabrik, Promonta. GMBH., Hamburg, Germany |
January 14, 1941 |
US2228561 |
| Reaction Epinephrine with amino acids and products thereof |
562/573 |
Preparation of addition compounds or “conjugates” of epinephrine with amino acids |
Richard G. Roberts |
___ |
March 10, 1942 |
US2275809 |
| Reaction of epinephrine with sterols and product thereof |
552/544 |
Preparation of addition compounds or “conjugates” of epinephrine with sterols |
Richard G. Roberts |
Armour and Company, Chicago |
November 2, 1943 |
US2333581 |
| Epinephrine derivatives and preparation thereof |
514/547 |
Epinephrine prolonged effectiveness and physiological activity |
Edwin L. Gustus |
Wilson and Co., Inc. |
October 19, 1943 |
US2332075 |
| Gelatin vehicle |
514/653 |
Retarding the absorption or activity of subcutaneously injected drugs and particularly epinephrine compounds |
Harold A. Abramson |
___ |
February 11, 1947 |
US2415719 |
| Urea stabilized epinephrine mist for treatment of asthma |
514/588 |
Compositions adapted for the nebulization therapy of asthma |
Herold Alexander Abramson |
___ |
April 11, 1950 |
US2503650 |
| Process for the purification of epinephrine |
564/361 |
The separation of the primary amine arterenol from the secondary amine epinephrine. |
Frank H. Tendick |
Parke Davis and Company, Detroit |
July 8, 1952 |
US2602818 |
| Therapeutic composition of procaine and adrenaline precursor |
514/536 |
Therapeutic composition and administering methods |
Manme E. Borsook |
Clinical Research Foundation |
October 23, 1956 |
US2768113 |
| Process for obtaining epinephrine free adrenal cortical hormones |
435/268 |
Obtaining Physiologically active substances by treatment of mammalian adrenal glands which may be used in treatment of diseases in humans due to dysfunction of endocrine glands |
Emil Gilbert Conason |
Schenley Industries, Inc., New York |
January 22, 1957 |
US2778770 |
| Self propelling compositions for inhalation therapy containing a salt of isoproterenol or epinephrine |
222/192 |
Overcoming vehicle of medicament shortcomings: rubber airbulb, irritation, fixed dosage. |
Irving Porush, George L. Mason |
Riker laboratories, Inc., Los Angeles. |
January 13, 1959 |
US2868691 |
| Stabilization of epinephrine |
514/653 |
Improving pH level of solution of epinephrine to prevent patient eye irritation |
Sidney Riegelman |
The Regents of the University of California |
September 15, 1964 |
US3149035 |
